Cell Structure, Function, and Motility
Hank W. Bass
Meiosis in higher plants; telomere dynamics; molecular cytology; maize chromatin, nuclease sensitivity profiling, G4-DNA, and genome research in maize and hop.
Brian P. Chadwick
X chromosome inactivation; chromatin organization; epigenetic gene regulation.
P. Bryant Chase
Biomechanics of cardiac and skeletal muscle.
Jonathan H. Dennis
The biology of chromatin involved in the innate immune response.
Muscle contraction; structure-function of proteins; cellular physiology.
Replication, Transcription and Genome Architecture in Stem Cells
Biological membranes; cell-substrate interactions; bionanotechnology.
M. Elizabeth Stroupe
The Stroupe laboratory uses cryogenic electron microscopy and X-ray crystallography to discover fundamental mechanisms in ribosome biogenesis and sulfur metabolism.
Kenneth A. Taylor
Macromolecular structure determination by 3-D electron microscopy; muscle, cytoskeleton and cell adhesion structure; virus structure.
Dr. Hong-Guo Yu
Molecular and cell biology of the yeast nucleus
Dr. Qian Yin
Biochemist and structural biologist dedicated to delineate individual proteins functions and their interactions in innate immunity, inflammation, pathogen-host interaction, and autophagy.
Kaposi's sarcoma-associated herpesvirus (KSHV); viral evasion of the host innate immune responses; viral modulation of the host kinase signaling pathways; role and assembly of KSHV tegument proteins.
Research groups offering graduate training in the area of Cell Structure, Function, and Motility focus their research efforts on understanding the molecular morphology and dynamics of nuclei, flagella, muscle, and nonmuscle cell motility systems. These groups use a variety of experimental approaches (e.g., sophisticated light & electron microscopy, molecular biology, genetics, protein biochemistry, NMR) to gain greater understanding of the structural components, molecular organization, assembly, and movement of dynamic systems in vertebrate and invertebrate animal cells, plant cells, and unicellular algae. The individual labs are well equipped and focused on graduate training. Graduate students are encouraged to use state-of-the-art equipment in the departmental Biological Science Imaging Resource (BSIR), Molecular Cloning Facility, Hybridoma Facility, and at the National High Magnetic Field Laboratory for their research projects.