Our research focuses on how genetic information is used and regulated at the molecular, cellular and, in some cases, whole-animal level. We utilize genetic mutants to define gene function in organisms ranging from microbes to mammals. Experimental approaches include classical genetic screens for phenotypic markers; molecular analyses of gene structure and function; gene identification, cloning, construction, and mapping; and assessment of molecular evolution, signal transduction, and gene activity. Inter-laboratory activities (e.g. joint lab meetings, departmental seminars, topical seminar series) promote faculty and student interactions and the critique of current research and the scientific literature. Close work with associated departments/programs (e.g. Chemistry Department, the Institute of Molecular Biophysics, Structural Biology Program, the National High Magnetic Field Laboratory) enhances the access to state-of-the-art research technologies provided by the Department of Biological Science core facilities. Emphasizing high-quality, nationally competitive research, our diverse laboratories provide balance and breadth in graduate and post-graduate training.