BIOLOGICAL
SCIENCE
FACULTY MEMBER
Dr. James M. Fadool
Office: 3018 King Life Sciences
| Office: | (850) 644-3550
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| Lab: | (850) 645-3348
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| Fax: | (850) 645-8447
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| Mail code: | 4295 |
| E-mail: |
jfadool@bio.fsu.edu
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Personal Home Page 
Associate Professor;
Ph.D., Michigan State University, 1992
Research and Professional Interests:
Vertebrate embryology, genetic and biochemical mechanisms regulating development and degenerative diseases of the visual system. Novel transgenic technologies for identification of transcriptionally active regions of the genome using the zebrafish as a model organism.
Selected Publications:
Fadool, J.M., Brockerhoff, S.E., Hyatt, G.A. and Dowling, J.E. (1997) Mutations affecting eye morphology in the developing zebrafish (Danio rerio). Dev. Genetics. 20:288-295.
[View abstract]
Fadool, J.M., Hartl, D.L. and Dowling, J.E. (1998) Transposition of the mariner element from Drosophila mauritiana in zebrafish (Danio rerio). Proc. Natl. Acad. Sci. USA 95:5182-5186.
[View abstract]
McCune, A.R., Fuller, R.C., Aquilina, A.A., Dawley, R.M., Fadool, J.M., Houle, D., Travis, J., Kondrashov, A.S. (2002) A low genomic number of recessive lethals in natural populations of bluefin killifish and zebrafish. Science 296:2398-401.
[View abstract]
Fadool, J.M. (2003) Development of a rod photoreceptor mosaic revealed in transgenic zebrafish. Dev. Biol. 258:277-290.
[View abstract]
DeCarvalho, A.C., Cappendijk, S. and Fadool, J.M. (2004) Expression of the Pou domain transcription factor, Brn3b in the lateral line and retina of zebrafish. Dev. Dynamics 229:869-876.
[View abstract]
Vihtelic T.S., Fadool, J.M., Thornton, K., Hyde, D.R., and Wistow, G. (2005) Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. Mol Vision. 11:1083-1100.
[View abstract]
Morris, A.C., Schroeter, E.H., Bilotta, J, Wong, R.O., and Fadool, J.M. (2005) Cone survival despite rod degeneration in transgenic zebrafish. Invest. Ophthalmol. Visual Sci. 46:4762-4771.
[View abstract]
Stearns, G., Evangelista, M., Fadool, J.M., and Brockerhoff, S.E. (2007) A mutation in the cone-specific pde6 gene causes rapid cone photoreceptor degeneration in zebrafish.
J Neurosci. 27:13866-74.
[View abstract]
Morris, A.C., Scholz, T.L., Brockerhoff, S.E., and Fadool, J.M. (2008) Genetic dissection reveals two separate pathways for rod and cone regeneration in the teleost retina. Dev Neurobiol. 68:605-19.
[View abstract]
Alvarez-Delfin, K., Morris, A.C., Snelson, C.D., Gamse, J.T., Gupta, T., Marlow, F.L., Mullins, M.C., Burgess, H.A., Granato, M., Fadool, J.M. (2009) Tbx2b is required for ultraviolet photoreceptor cell specification during zebrafish retinal development. Proc Natl Acad Sci U S A. 106:2023-2028.
[View abstract]
Postdoctoral Associates:
Morris, Ann C.
Graduate Students:
Alvarez-Delfin, Karen
Millet, Alisa
Pflueger, Melissa
Pope, Ben
Saade, Carole
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