Dr. James M. Fadool —FSU Biological Science Faculty Member -->
BIOLOGICAL SCIENCE
FACULTY MEMBER

Dr. James M. Fadool

Office: 3018 King Life Sciences
Office: (850) 644-3550
Lab: (850) 645-3348
Fax: (850) 645-8447
Mail code: 4295
E-mail: jfadool@bio.fsu.edu

Lab Home Page

Associate Professor
Ph.D., Michigan State University, 1992 PostDoc, Harvard University
Graduate Faculty Status

Dr. James Fadool is currently recruiting new graduate students for Fall 2014.

Research and Professional Interests:

Vertebrate embryology, genetic and biochemical mechanisms regulating development and degenerative diseases of the visual system. Novel transgenic technologies for identification of transcriptionally active regions of the genome using the zebrafish as a model organism.

Selected Publications:

Saade, C. J., K. Alvarez-Delfin, and J. M. Fadool (2013) Rod photoreceptors protect from cone degeneration-induced retinal remodeling and restore visual responses in zebrafish.. J Neurosci 33: 1804-1814.
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Morris, A. C., M. A. Forbes-Osborne, L. S. Pillai, and J. M. Fadool (2011) Microarray analysis of XOPS-mCFP zebrafish retina identifies genes associated with rod photoreceptor degeneration and regeneration.. Invest Ophthalmol Vis Sci. 52: 2255-2266.
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Alvarez-Delfin, K., A. C. Morris, C. D. Snelson, J. T. Gamse, T. Gupta, F. L. Marlow, M. C. Mullins, H. A. Burgess, M. Granato, and J. M. Fadool (2009) Tbx2b is required for ultraviolet photoreceptor cell specification during zebrafish retinal development. Proc Natl Acad Sci USA. 106: 2023-2028.
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Morris, A. C., T. L. Scholz, S. E. Brockerhoff, and J. M. Fadool (2008) Genetic dissection reveals two separate pathways for rod and cone regeneration in the teleost retina. Dev Neurobiol. 68: 605-619.
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Stearns, G., M. Evangelista, J. M. Fadool, and S. E. Brockerhoff (2007) A mutation in the cone-specific pde6 gene causes rapid cone photoreceptor degeneration in zebrafish. J Neurosci. 27: 13866-74.
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Vihtelic, T. S., F. J. M, T. K. A, and H. D. R (2005) Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. . Mol Vision 13: 1083-1100.
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Morris, A. C., S. E. H, W. R. O, and F. J. M (2005) Cone survival despite rod degeneration in XOPS-mCFP transgenic zebrafish.. Invest Ophthalmol Vis Sci. 46: 4762-71.
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DeCarvalho, A. C., S. Cappendijk, and J. M. Fadool (2004) Expression of the Pou domain transcription factor, Brn3b in the lateral line and retina of zebrafish. Dev. Dynamics 229: 869-876.
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Fadool, J. M. (2003) Development of a rod photoreceptor mosaic revealed in transgenic zebrafish. Dev. Biol. 258: 277-290.
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McCune, A. R., R. C. Fuller, A. A. Aquilina, R. M. Dawley, J. M. Fadool, D. Houle, J. Travis, and A. S. Kondrashov (2002) A low genomic number of recessive lethals in natural populations of bluefin killifish and zebrafish. Science 296: 2398-401.
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Fadool, J. M., D. L. Hartl, and J. E. Dowling (1998) Transposition of the mariner element from Drosophila mauritiana in zebrafish (Danio rerio). Proc. Natl. Acad. Sci. USA 95: 5182-5186.
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Fadool, J. M., S. E. Brockerhoff, G. A. Hyatt, and J. E. Dowling (1997) Mutations affecting eye morphology in the developing zebrafish (Danio rerio). Dev. Genetics 20: 288-295.
(View abstract

Graduate Students:

Benoit, Chelsea
Rajkumari, Gayatri
Sotolongo-Lopez, Mailin

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