BIOLOGICAL SCIENCE
FACULTY MEMBER
Dr. Darin R Rokyta
| Office: | 4058 King Life Sciences
|
| Office: | (850) 645-8812
|
| Lab: | (850) 645-8817
|
| Fax: | (850) 645-8447
|
| Mail code: | 4295 |
| E-mail: |
drokyta@bio.fsu.edu
|
Assistant Professor;
Ph.D., University of Idaho, 2006
POSITIONS AVAILABLE for postdoctoral investigators, graduate students, and undergraduate students (starting in 2008).
Research and Professional Interests:
My research investigates the molecular and statistical properties of adaptive evolution.
The overarching goal of my work is to develop a robust, quantitative model of adaptive
evolution at the molecular level and the statistical methology to test the model predictions
and assumptions, but the available empirical data are insufficient for evaluating the
strengths and weaknesses of current models and guiding future efforts. My research therefore
also involves generating empirical data sets using experimental evolution approaches.
Selected Publications:
Joyce, P., D. R. Rokyta, C. J. Beisel, and H. A. Orr. 2008. A general extreme value
theory model for the adaptation of DNA sequences under strong selection and weak mutation.
Genetics 180:1627-1643.
Rokyta, D. R., C. J. Beisel, P. Joyce, M. T. Ferris, C. L. Burch, and H. A. Wichman. 2008. Beneficial fitness effects are not exponential for two viruses. Journal of Molecular Evolution 67:368-376.
Beisel, C. J., D. R. Rokyta, H. A. Wichman, and P. Joyce. 2007. Testing the extreme value domain of attraction for distributions of beneficial fitness effects. Genetics 176:2441-2449.
Rokyta, D. R., C. J. Beisel, and P. Joyce. 2006. Properties of adaptive walks on uncorrelated landscapes under strong selection and weak mutation. Journal of Theoretical Biology 243:114–120.
Rokyta DR, Burch CL, Caudle SB, Wichman HA. 2006. Horizontal gene transfer and the
evolution of microvirid coliphage genomes. Journal of Bacteriology 188:1134–1142. (featured
on the cover)
Rokyta, D. R., P. Joyce, S. B. Caudle, and H. A. Wichman. 2005. An empirical test of the mutational landscape model of adaptation using a single-stranded DNA virus. Nature Genetics 37: 441–444 (featured in News and Views).
Bull, J. J., M. R. Badgett, D. Rokyta, and I. J. Molineux. 2003. Experimental evolution yields hundreds of mutations in a functional viral genome. Journal of Molecular Evolution 57:241–248.
Rokyta, D., M. R. Badgett, I. J. Molineux, and J. J. Bull. 2002. Experimental genomic evolution: extensive compensation for loss of DNA ligase activity in a virus. Molecular Biology and Evolution 19:230–238.
|
:
External sites will open in a new browser window.