Biological Science Faculty Member
Dr. Lisa C. Lyons
Ph.D., University of Houston, 2000
Graduate Faculty Status
Research and Professional Interests:
Signaling and circadian modulation regulating associative memory
Selected Publications:Krishnan, H., Gandour, C., Ramos, J., Wrinkle, M., Sanchez-Pacheco, J., & Lyons, L. (2016). Acute Sleep Deprivation Blocks Short and Long-Term Operant Memory in Aplysia. Sleep, 39 (12), 12.
Lyons, L., Gardner, J., Gandour, C., & Krishnan, H. (2016). Role of proteasome dependent protein degradation in long-term operant memory in Aplysia. Learning and Memory, 15(24), 59-64.
Lyons, L., Gardner, J., Lentsch, C., Gandour, C., Krishnan, H., & Noakes, E. (2016). Differential role of calpain-dependent protein cleavage in intermediate and long-term operant memory in Aplysia. Neurobiology of Learning and Memory, 137, 134-141.
Krishnan, H., Noakes, E., & Lyons, L. (2016). Chronic Sleep Deprivation Differentially Affects Short and Long-term Operant Memory in Aplysia. Neurobiology of Learning and Memory, 134B, 349-359.
De Nobrega, A. K., & Lyons, L. (2016). Circadian Modulation of Alcohol-Induced Sedation and Recovery in Male and Female Drosophila. Journal of Biological Rhythms, 31(2), 142-160. doi:10.1177/0748730415627067.
Krishnan, H.C. and Lyons, L.C. (2015) Synchrony and desynchrony in circadian clocks: impacts on learning and memory. Learning and Memory. 22(9):426-437.
Vorster, Albrecht P. A.; Krishnan, Harini C.; BSc; Cirelli, Chiara; MD, PhD; Lyons, Lisa C. 2014. Characterization of sleep in Aplysia californica. Sleep. 37 (9):1453-1463.
Michel, M. and Lyons, L.C. 2014. Unraveling the complexities of circadian and sleep interactions with memory formation through invertebrate research. Frontiers in Systems Neuroscience. 8:133. doi: 10.3389/fnsys.2014.00133
van der Linde K, Fumagalli E, Roman G, Lyons LC. 2014. The FlyBar: Administering Alcohol to Flies. Journal of Visualized Experiments May 18; (87).
Michel M, Gardner JS, Green CL, Organ CL, Lyons LC. 2013. Protein phosphatase-dependent circadian regulation of intermediate-term associative memory. Journal of Neuroscience 33(10): 4605-13.
Winbush A, Reed D, Chang PL, Nuzhdin SV, Lyons LC, Arbeitman MN. 2012. Identification of gene expression changes associated with long-term memory of courtship rejection in Drosophila males. G3 2(11):1437-45.
Michel, M., C. L. Green, J. S. Gardner, C. L. Organ, and L. C. Lyons. 2012. Massed training induced intermediate term operant memory in Aplysia requires protein synthesis and multiple persistent kinase cascades. Journal of Neuroscience. 32(13):4581-91.
Lyons L. C. 2011. Critical role of the circadian clock in memory formation: lessons from Aplysia. Frontiers in Molecular Neuroscience 4:52.
Michel, M., C. L. Green, A. Eskin, and L. C. Lyons. 2011. PKG-mediated MAPK signaling is necessary for long-term operant memory in Aplysia. Learning and Memory 18:108-117.
van der Linde, K., and L. C. Lyons. 2011. Circadian modulation of acute alcohol sensitivity but not acute tolerance in Drosophila. Chronobiology International 28:397-406.
Levitan, D., R. Twitto, R. Levy, L. C. Lyons, and A. J. Susswein. 2010. A brief retraining regulates the persistence and lability of a long-term memory. Learning and Memory 17:402-406.
Michel, M., C. L. Green, and L. C. Lyons. 2010. PKA and PKC are required for long-term but not short-term in vivo operant memory in Aplysia. Learning and Memory 18:19-23.
Lyons, L. C., and G. Roman. 2009. Circadian modulation of short-term memory in Drosophila. Learning and Memory 16:19-27.
Gerstner, J. R., L. C. Lyons, K. P. Wright, Jr., D. H. Loh, O. Rawashdeh, K. L. Eckel-Mahan, and G. W. Roman. 2009. Cycling behavior and memory formation. Journal of Neuroscience 29:12824-12830.
Levitan, D., L. C. Lyons, A. Perelman, C. L. Green, B. Motro, A. Eskin, and A. J. Susswein. 2008. Training with inedible food in Aplysia causes expression of C/EBP in the buccal but not cerebral ganglion. Learning and Memory 15:412-416.
Lyons, L. C., C. L. Green, and A. Eskin. 2008. Intermediate-term memory is modulated by the circadian clock. Journal of Biological Rhythms 23:538-542.
Collado, M. S., L. C. Lyons, J. M. Levenson, J. D. Pita-Almenar, O. Khabour, L. Schrader, and A. Eskin. 2007. In vivo regulation of an Aplysia glutamate transporter, APGT1, during long-term memory formation. Journal of Neurochemistry 100:1315-1328.
Lyons, L. C., O. Rawashdeh, and A. Eskin. 2006. Non-ocular circadian oscillators and photoreceptors modulate long-term memory formation in Aplysia. Journal of Biological Rhythms 21:245-255.
Lyons, L. C., M. S. Collado, O. Khabour, C. L. Green, and A. Eskin. 2006. The circadian clock modulates core steps in long-term memory formation in Aplysia. Journal of Neuroscience 26:8662-8671.
Lyons, L. C., O. Rawashdeh, A. Katzoff, A. J. Susswein, and A. Eskin. 2005. Circadian modulation of complex learning in diurnal and nocturnal Aplysia. Proceedings of the National Academy of Sciences of the USA 102:12589-12594.