Biological Science Faculty Member
Dr. Erdem Bangi
Ph.D., Brown University, 2005
Graduate Faculty Status
Research and Professional Interests:
My laboratory takes a novel and innovative approach to studying colorectal cancer by leveraging sophisticated genetic tools and practical advantages of Drosophila. We build, study and drug-screen Drosophila cancer models that reflect the complexity and diversity of sequenced human tumors.
Current reasearch interests include:
-- studying early steps of intestinal tumorigenesis by genetically manipulating fly orthologs of genes frequently mutated in human colon tumors (both in the larval and the adult intestine)
-- developing new genetic tools and strategies to incorporate more genetic complexity into our tumor models
-- using our models to explore drug mechanisms of action and resistance, identify drug targets, new drugs, and drug combinations that may be effective against genetically complex tumors.