Cell Structure, Function, and Motility
Hank W. Bass
Telomeres, meiosis, and chromatin structure in maize through genetics, genomics, and 3D molecular cytology.
Brian P. Chadwick
X chromosome inactivation; chromatin organization; epigenetic gene regulation.
P. Bryant Chase
Biomechanics of cardiac and skeletal muscle.
Intercellular communication in Drosophila egg chambers, growth and proliferation control and cancer models, cell competition.
Jonathan H. Dennis
The biology of chromatin involved in the innate immune response.
W. Ross Ellington
Biochemical adaptation; enzyme structure, function, and evolution.
Muscle contraction; structure-function of proteins; cellular physiology.
Structure and replication of chromosomes in stem cells and cancer.
Laura R. Keller
Molecular genetics; signal transduction and regulation of gene expression.
Thomas C.S. Keller
Cell and molecular biology of the cytoskeleton; cytoskeleton regulation and energetics.
Biological membranes; cell-substrate interactions; bionanotechnology.
M. Elizabeth Stroupe
High-resolution cryogenic electron microscopy of proteins involved in cell structure and motility.
Kenneth A. Taylor
Macromolecular structure determination by 3-D electron microscopy; muscle, cytoskeleton and cell adhesion structure.
Dr. Hong-Guo Yu
Chromosome structural formation, meiotic recombination and genomic integrity.
Research groups offering graduate training in the area of Cell Structure, Function, and Motility focus their research efforts on understanding the molecular morphology and dynamics of nuclei, flagella, muscle, and nonmuscle cell motility systems. These groups use a variety of experimental approaches (e.g., sophisticated light & electron microscopy, molecular biology, genetics, protein biochemistry, NMR) to gain greater understanding of the structural components, molecular organization, assembly, and movement of dynamic systems in vertebrate and invertebrate animal cells, plant cells, and unicellular algae. The individual labs are well equipped and focused on graduate training. Graduate students are encouraged to use state-of-the-art equipment in the departmental Biological Science Imaging Resource (BSIR), Molecular Cloning Facility, Hybridoma Facility, and at the National High Magnetic Field Laboratory for their research projects.