Instructor Presentation Files

• Basic Electricity, Ionic Equilibrium, & Nernst and Goldman Equations
• Classical Biophysics (Squid Giant Axon) and Introduction to Voltage-gated Ion Channels
• The Diversity of Voltage-gated Ion Channels
• Patch-clamp Electrophysiology Technique
• DREADDS Technique
• Automated Patch-clamp Technique

Student/Instructor Presentation Files

• Resources Being Generated from Fall 2021 Class

  • Voltage-gated K Ion Channels
  • Ligand-gated Channels
  • Voltage-gated Na Ion Channels
  • Non-Selective Cation Channels
  • Piezo and Trp Channels
  • Aquaporins
  • DREADDS
  • In Vivo Electrophysiology
  • Viral Infection Strategies
  • Optogenetics
  • Genetically Incoded Optical Sensors
  • Cryo EM
  • Nucleopore Complex

• Resources Archived from Fall 2018 Class

  • Voltage-gated K Ion Channels - Slide Set 1
  • Voltage-gated K Ion Channels - Slide Set 2
  • Ligand-gated Ion Channels
  • Voltage-gated Sodium Ion Channels
  • Voltage-gated Calcium Ion Channels
  • Mechanical Ion Channels
  • Chloride Ion Channels
  • NMR and MRI Techniques
  • In Vivo Electrophysiology Techniques
  • Optogenetic Techniques
  • SPR and QCM Techniques
  • Cyro EM Techniques

• Archived Resources from Fall 2014 Class

  • Ligand Gated Ion Channel
  • Second-messenger Gated Ion Channel
  • Sodium Ion Channel
  • Potassium Ion Channel
  • Chloride Ion Channel
  • Calcium Ion Channel
  • Optogenetics
  • Dynamic Clamp
  • Functional Magnetic Resonance Imaging (fMRI)
  • X-ray Crystallography

• Resources Archived from Fall 2011 Class

  • Sodium Ion Channel
  • Potassium Ion Channel
  • Chloride Ion Channel
  • Ligand Gated Ion Channel
  • TRP Family of Ion Channel
  • Calcium Ion Channel
  • Optogenetics
  • Caged Compounds
  • Multi-electrode Arrays
  • Voltametry
  • In Vivo Recording Approaches
  • MNR of Ion Channel Proteins

• Resources Archived from Fall 2007 Class

  • Sodium Ion Channel
  • Potassium Ion Channel
  • Chloride Ion Channel
  • Neurotransmitter-gated Ion Channel
  • Second-messenger Gated Ion Channel
  • Calcium Ion Channel
  • Patch-clamp Electrophysiology Technique
  • Calcium Imaging and Voltage-sensitive Dye Recordings
  • Multi-electrode Arrays
  • Protein Co-Localization Approaches: Biochemical, Optical, and Biophysical
  • X-Ray Crystallography Applied to Ion Channel Structure: Preparation of Sample
  • X-Ray Crystallography Applied to Ion Channel Structure: Mathematical Basis & Structure Determination

• Archived Resources from Fall 2005 Class

  • Sodium Ion Channel
  • Potassium Ion Channel
  • Choride Ion Channel
  • ACh Receptor
  • Second Messenger-gated Ion Channel
  • Calcium Ion Channel
  • Patch-clamp Electrophysiology Technique
  • Calcium Imaging, Caged Compounds, and Voltage-sensitive Dyes
  • Multi-electrode Arrays and in Vivo Recordings
  • Atomic Force Microscopy for Ion Channel Localization
  • Crystallography Applied to Ion Channel Structure
  • Fluorescence Resonance Energy Transfer Applied to Channel Interactions

Annotated Bibliography Files

• Resources Being Generated from Fall 2021 Class

  • Voltage-gated K Ion Channels
  • Voltage-gated Na Ion Channels
  • Non-selective Cation Ion Channels
  • Piezo and Trp Ion Channels
  • Aquaporins
  • DREADDS
  • In Vivo Electrophysiology
  • Viral Infection Strategies
  • CryoEM Crystallography
  • Optogenetics
  • Genetically Incoded Optical Sensors
  • Nucleopore Complex

• Resources Archived from Fall 2018 Class

  • Voltage-gated K Ion Channels
  • Ligand-gated Ion Channel - Part I
  • Ligand-gated Ion Channel - Part II
  • Sodium Ion Channel
  • Calcium Ion Channel
  • Mechanical Ion Channel - Part 1
  • Mechanical Ion Channel - Part 2
  • Chloride Ion Channel - Part 1
  • Chloride Ion Channel - Part 2
  • NMR/MRI Technique - Part 1
  • NMR/MRI Technique - Part 2
  • In Vivo Electrophysiology Technique - Part 1
  • In Vivo Electrophysiology Technique - Part 2
  • Optogenetics Technique - Part 1
  • Optogenetics Technique - Part 2
  • Surface Plasmon Resonance/Quartz Crystal Microbalance Technique - Part 2
  • Cryo EM Technique - Part 1
  • Cryo EM Technique - Part 2

• Resources Archived from Fall 2014 Class

  • Ligand-gated Ion Channel
  • Second Messenger Gated Ion Channel - Part 1
  • Second Messenger Gated Ion Channel - Part 2
  • Sodium Ion Channel - Part 1
  • Sodium Ion Channel - Part 2
  • Potassium Ion Channel - Part 1
  • Potassium Ion Channel - Part 2
  • Chloride Ion Channel - Part 2
  • Chloride Ion Channel - Part 2
  • Calcium Ion Channel - Part 1
  • Calcium Ion Channel - Part 2
  • Optogenetics - Part 1
  • Optogenetics - Part 2
  • Dynamic Clamp - Part 1
  • Dynamic Clamp - Part 2
  • Dynamic Clamp - Part 3
  • fMRI

• Resources Archived from Fall 2011 Class

  • Sodium Ion Channel - Part 1
  • Sodium Ion Channel - Part 2
  • Potassium Ion Channel - Part 1
  • Potassium Ion Channel - Part 2
  • Chloride Ion Channel - Part 1
  • Chloride Ion Channel - Part 2
  • Ligand-gated Ion Channel - Part 1
  • Ligand-gated Ion Channel - Part 2
  • Ligand-gated Ion Channel - Part 3
  • TRP Family of Ion Channel - Part 1
  • TRP Family of Ion Channel - Part 2
  • Calcium Ion Channel - Part 1
  • Calcium Ion Channel - Part 2
  • Calcium Ion Channel - Part 3
  • Cage Compounds
  • Optogenetics - Part 1
  • Optogenetics - Part 2
  • Multi-electrode Arrays - Part 1
  • Multi-electrode Arrays - Part 2
  • Multi-electrode Arrays - Part 3
  • Voltametry - Part 1
  • Voltametry - Part 2
  • Voltametry - Part 3
  • In Vivo Recording Approaches - Part 1
  • In Vivo Recording Approaches - Part 2
  • In Vivo Recording Approaches - Part 3
  • NMR of Ion Channel Proteins - Part 1
  • NMR of Ion Channel Proteins - Part 2
  • NMR of Ion Channel Proteins - Part 3
  • NMR of Ion Channel Proteins - Part 4

• Resources Archived from Fall 2007 Class

  • Sodium Ion Channel
  • Potassium Ion Channel
  • Chloride Ion Channel
  • Neurotransmitter-gated Ion Channel
  • Second-messenger Gated Ion Channel
  • Calcium Ion Channel
  • Calcium Imaging
  • Voltage-sensitive Dye Recordings
  • Mutagenesis to Determine Structure/Function
  • In Vitro Multi-electroarrays
  • In Vivo Multi-electroarrays
  • X-ray Crystallography: Preparation of Sample
  • X-ray Crystallography: Mathematical Basis & Structure Determination

• Archived Resources from Fall 2005 Class

  • Sodium Ion Channel
  • Potassium Ion Channel
  • Choride Ion Channel
  • ACh Receptor
  • Second Messenger-gated Ion Channel
  • Calcium Ion Channel
  • Patch-clamp Electrophysiology Technique
  • Calcium Imaging, Caged Compounds, and Voltage-sensitive Dyes
  • Multi-electrode Arrays and in Vivo Recordings
  • Atomic Force Microscopy for Ion Channel Localization
  • Crystallography Applied to Ion Channel Structure
  • Fluorescence Resonance Energy Transfer Applied to Channel Interactions