Ashley Culver-Cochran Ph.D is a recent graduate of the CMB doctoral program where she worked in Dr. Brian Chadwick’s laboratory. Her research focused on the function of the chromatin remodeling protein William's Syndrome Transcription Factor (WSTF). Using cutting-edge genome engineering techniques, Ashley targeted the gene for WSTF resulting in a human knockout cell-based model. Her findings were recently published in BMC Genomics, and form the foundation for future WSTF-based research projects.
Article: Culver-Cochran A.E. and Chadwick B.P. (2013) "Loss of WSTF results in spontaneous fluctuations of heterochromatin formation and resolution, combined with substantial changes to gene expression." BMC Genomics 14:740.